Defeating Alzheimer's disease and other dementias: a priority for European science and society.
Identifieur interne : 002123 ( Main/Exploration ); précédent : 002122; suivant : 002124Defeating Alzheimer's disease and other dementias: a priority for European science and society.
Auteurs : Bengt Winblad [Suède] ; Philippe Amouyel [France] ; Sandrine Andrieu [France] ; Clive Ballard [Royaume-Uni] ; Carol Brayne [Royaume-Uni] ; Henry Brodaty [Australie] ; Angel Cedazo-Minguez [Suède] ; Bruno Dubois [France] ; David Edvardsson [Suède] ; Howard Feldman [Canada] ; Laura Fratiglioni [Suède] ; Giovanni B. Frisoni [Italie] ; Serge Gauthier [Canada] ; Jean Georges [Luxembourg (pays)] ; Caroline Graff [Suède] ; Khalid Iqbal [États-Unis] ; Frank Jessen [Allemagne] ; Gunilla Johansson [Suède] ; Linus Jönsson [Suède] ; Miia Kivipelto [Suède] ; Martin Knapp [Royaume-Uni] ; Francesca Mangialasche [Suède] ; René Melis [Pays-Bas] ; Agneta Nordberg [Suède] ; Marcel Olde Rikkert [Pays-Bas] ; Chengxuan Qiu [Suède] ; Thomas P. Sakmar [États-Unis] ; Philip Scheltens [Pays-Bas] ; Lon S. Schneider [États-Unis] ; Reisa Sperling [États-Unis] ; Lars O. Tjernberg [Suède] ; Gunhild Waldemar [Danemark] ; Anders Wimo [Suède] ; Henrik Zetterberg [Royaume-Uni]Source :
- The Lancet. Neurology [ 1474-4465 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
- organisation et administration : Recherche biomédicale.
- économie : Recherche biomédicale.
- Démence, Europe, Humains, Maladie d'Alzheimer.
English descriptors
- KwdEn :
- MESH :
- geographic : Europe.
- economics : Biomedical Research.
- organization & administration : Biomedical Research.
- therapy : Alzheimer Disease, Dementia.
- Humans.
DOI: 10.1016/S1474-4422(16)00062-4
PubMed: 26987701
Affiliations:
- Allemagne, Australie, Canada, Danemark, France, Italie, Luxembourg (pays), Pays-Bas, Royaume-Uni, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Californie, District de Cologne, Grand Londres, Gueldre, Hauts-de-France, Hollande-Septentrionale, Hovedstaden, Massachusetts, Midi-Pyrénées, Nord-Pas-de-Calais, Occitanie (région administrative), Rhénanie-du-Nord-Westphalie, Svealand, État de New York, Île-de-France
- Amsterdam, Bonn, Cambridge, Copenhague, Lille, Londres, Los Angeles, Nimègue, Paris, Stockholm, Toulouse
- Université de Californie du Sud, Université de Cambridge
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Le document en format XML
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Electronic address: bengt-winblad-swedishbrainpower@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><affiliation wicri:level="3"><nlm:affiliation>Centre Hospitalier Régional Universitaire de Lille, Institut Pasteur de Lille, INSERM U1167 RID-AGE, Unité d'Epidémiologie et de Santé Publique, Labex DISTALZ, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Hospitalier Régional Universitaire de Lille, Institut Pasteur de Lille, INSERM U1167 RID-AGE, Unité d'Epidémiologie et de Santé Publique, Labex DISTALZ, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Andrieu, Sandrine" sort="Andrieu, Sandrine" uniqKey="Andrieu S" first="Sandrine" last="Andrieu">Sandrine Andrieu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology and Public Health, Faculty of Medicine, Toulouse University Hospital, Toulouse, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Epidemiology and Public Health, Faculty of Medicine, Toulouse University Hospital, Toulouse</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Ballard, Clive" sort="Ballard, Clive" uniqKey="Ballard C" first="Clive" last="Ballard">Clive Ballard</name><affiliation wicri:level="3"><nlm:affiliation>Wolfson Centre for Age-Related Diseases, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wolfson Centre for Age-Related Diseases, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Brayne, Carol" sort="Brayne, Carol" uniqKey="Brayne C" first="Carol" last="Brayne">Carol Brayne</name><affiliation wicri:level="4"><nlm:affiliation>Cambridge Institute of Public Health, University of Cambridge, Cambridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cambridge Institute of Public Health, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Brodaty, Henry" sort="Brodaty, Henry" uniqKey="Brodaty H" first="Henry" last="Brodaty">Henry Brodaty</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing and Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Healthy Brain Ageing and Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Cedazo Minguez, Angel" sort="Cedazo Minguez, Angel" uniqKey="Cedazo Minguez A" first="Angel" last="Cedazo-Minguez">Angel Cedazo-Minguez</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name><affiliation wicri:level="3"><nlm:affiliation>Institut de la Mémoire et de la Maladie d'Alzheimer, IM2A, INSERM, Institut du Cerveau et de la Moelle Épinière, UMR-S975, Groupe Hospitalier Pitié-Salpêtrière, Université Pierre et Marie Curie-Paris 6, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut de la Mémoire et de la Maladie d'Alzheimer, IM2A, INSERM, Institut du Cerveau et de la Moelle Épinière, UMR-S975, Groupe Hospitalier Pitié-Salpêtrière, Université Pierre et Marie Curie-Paris 6, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Edvardsson, David" sort="Edvardsson, David" uniqKey="Edvardsson D" first="David" last="Edvardsson">David Edvardsson</name><affiliation wicri:level="1"><nlm:affiliation>School of Nursing and Midwifery, La Trobe University, Melbourne, VIC, Australia; Department of Nursing, Umeå University, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>School of Nursing and Midwifery, La Trobe University, Melbourne, VIC, Australia; Department of Nursing, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Feldman, Howard" sort="Feldman, Howard" uniqKey="Feldman H" first="Howard" last="Feldman">Howard Feldman</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Neurology, Faculty of Medicine, University of British Columbia, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Fratiglioni, Laura" sort="Fratiglioni, Laura" uniqKey="Fratiglioni L" first="Laura" last="Fratiglioni">Laura Fratiglioni</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Frisoni, Giovanni B" sort="Frisoni, Giovanni B" uniqKey="Frisoni G" first="Giovanni B" last="Frisoni">Giovanni B. Frisoni</name><affiliation wicri:level="1"><nlm:affiliation>Geneva University Hospitals and University of Geneva, Geneva, Switzerland; IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Geneva University Hospitals and University of Geneva, Geneva, Switzerland; IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia</wicri:regionArea><wicri:noRegion>Brescia</wicri:noRegion></affiliation></author><author><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name><affiliation wicri:level="1"><nlm:affiliation>McGill Center for Studies in Aging, Alzheimer's Disease Research Unit, and Douglas Mental Health University Institute, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McGill Center for Studies in Aging, Alzheimer's Disease Research Unit, and Douglas Mental Health University Institute, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Georges, Jean" sort="Georges, Jean" uniqKey="Georges J" first="Jean" last="Georges">Jean Georges</name><affiliation wicri:level="1"><nlm:affiliation>Alzheimer Europe, Luxembourg City, Luxembourg.</nlm:affiliation><country xml:lang="fr">Luxembourg (pays)</country><wicri:regionArea>Alzheimer Europe, Luxembourg City</wicri:regionArea><wicri:noRegion>Luxembourg City</wicri:noRegion></affiliation></author><author><name sortKey="Graff, Caroline" sort="Graff, Caroline" uniqKey="Graff C" first="Caroline" last="Graff">Caroline Graff</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Iqbal, Khalid" sort="Iqbal, Khalid" uniqKey="Iqbal K" first="Khalid" last="Iqbal">Khalid Iqbal</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research, Staten Island, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research, Staten Island, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Jessen, Frank" sort="Jessen, Frank" uniqKey="Jessen F" first="Frank" last="Jessen">Frank Jessen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry, University of Cologne, Cologne, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Psychiatry, University of Cologne, Cologne, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Johansson, Gunilla" sort="Johansson, Gunilla" uniqKey="Johansson G" first="Gunilla" last="Johansson">Gunilla Johansson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Jonsson, Linus" sort="Jonsson, Linus" uniqKey="Jonsson L" first="Linus" last="Jönsson">Linus Jönsson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Kivipelto, Miia" sort="Kivipelto, Miia" uniqKey="Kivipelto M" first="Miia" last="Kivipelto">Miia Kivipelto</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Knapp, Martin" sort="Knapp, Martin" uniqKey="Knapp M" first="Martin" last="Knapp">Martin Knapp</name><affiliation wicri:level="3"><nlm:affiliation>Personal Social Services Research Unit, London School of Economics and Political Science, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Personal Social Services Research Unit, London School of Economics and Political Science, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Mangialasche, Francesca" sort="Mangialasche, Francesca" uniqKey="Mangialasche F" first="Francesca" last="Mangialasche">Francesca Mangialasche</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Melis, Rene" sort="Melis, Rene" uniqKey="Melis R" first="René" last="Melis">René Melis</name><affiliation wicri:level="3"><nlm:affiliation>Radboudumc Alzheimer Centre and Department of Geriatric Medicine, Radboud University Medical Center, Nijmegen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboudumc Alzheimer Centre and Department of Geriatric Medicine, Radboud University Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Nordberg, Agneta" sort="Nordberg, Agneta" uniqKey="Nordberg A" first="Agneta" last="Nordberg">Agneta Nordberg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Translational Alzheimer Biology, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Translational Alzheimer Biology, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Rikkert, Marcel Olde" sort="Rikkert, Marcel Olde" uniqKey="Rikkert M" first="Marcel Olde" last="Rikkert">Marcel Olde Rikkert</name><affiliation wicri:level="3"><nlm:affiliation>Radboudumc Alzheimer Centre and Department of Geriatric Medicine, Radboud University Medical Center, Nijmegen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboudumc Alzheimer Centre and Department of Geriatric Medicine, Radboud University Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Qiu, Chengxuan" sort="Qiu, Chengxuan" uniqKey="Qiu C" first="Chengxuan" last="Qiu">Chengxuan Qiu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Sakmar, Thomas P" sort="Sakmar, Thomas P" uniqKey="Sakmar T" first="Thomas P" last="Sakmar">Thomas P. Sakmar</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Laboratory of Chemical Biology & Signal Transduction, The Rockefeller University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Laboratory of Chemical Biology & Signal Transduction, The Rockefeller University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Scheltens, Philip" sort="Scheltens, Philip" uniqKey="Scheltens P" first="Philip" last="Scheltens">Philip Scheltens</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus, Amsterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Schneider, Lon S" sort="Schneider, Lon S" uniqKey="Schneider L" first="Lon S" last="Schneider">Lon S. Schneider</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry and the Behavioral Sciences and Department of Neurology, Keck School of Medicine, Leonard Davis School of Gerontology of the University of Southern California, Los Angeles, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry and the Behavioral Sciences and Department of Neurology, Keck School of Medicine, Leonard Davis School of Gerontology of the University of Southern California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Sperling, Reisa" sort="Sperling, Reisa" uniqKey="Sperling R" first="Reisa" last="Sperling">Reisa Sperling</name><affiliation wicri:level="2"><nlm:affiliation>Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Tjernberg, Lars O" sort="Tjernberg, Lars O" uniqKey="Tjernberg L" first="Lars O" last="Tjernberg">Lars O. Tjernberg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Waldemar, Gunhild" sort="Waldemar, Gunhild" uniqKey="Waldemar G" first="Gunhild" last="Waldemar">Gunhild Waldemar</name><affiliation wicri:level="3"><nlm:affiliation>Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Wimo, Anders" sort="Wimo, Anders" uniqKey="Wimo A" first="Anders" last="Wimo">Anders Wimo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Zetterberg, Henrik" sort="Zetterberg, Henrik" uniqKey="Zetterberg H" first="Henrik" last="Zetterberg">Henrik Zetterberg</name><affiliation wicri:level="3"><nlm:affiliation>Clinical Neurochemistry Laboratory, Department of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; UCL Institute of Neurology, Queen Square, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Neurochemistry Laboratory, Department of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; UCL Institute of Neurology, Queen Square, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:26987701</idno><idno type="pmid">26987701</idno><idno type="doi">10.1016/S1474-4422(16)00062-4</idno><idno type="wicri:Area/PubMed/Corpus">002045</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002045</idno><idno type="wicri:Area/PubMed/Curation">002020</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002020</idno><idno type="wicri:Area/PubMed/Checkpoint">002020</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002020</idno><idno type="wicri:Area/Ncbi/Merge">003296</idno><idno type="wicri:Area/Ncbi/Curation">003296</idno><idno type="wicri:Area/Ncbi/Checkpoint">003296</idno><idno type="wicri:Area/Main/Merge">002122</idno><idno type="wicri:Area/Main/Curation">002123</idno><idno type="wicri:Area/Main/Exploration">002123</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Defeating Alzheimer's disease and other dementias: a priority for European science and society.</title><author><name sortKey="Winblad, Bengt" sort="Winblad, Bengt" uniqKey="Winblad B" first="Bengt" last="Winblad">Bengt Winblad</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden. Electronic address: bengt-winblad-swedishbrainpower@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><affiliation wicri:level="3"><nlm:affiliation>Centre Hospitalier Régional Universitaire de Lille, Institut Pasteur de Lille, INSERM U1167 RID-AGE, Unité d'Epidémiologie et de Santé Publique, Labex DISTALZ, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Hospitalier Régional Universitaire de Lille, Institut Pasteur de Lille, INSERM U1167 RID-AGE, Unité d'Epidémiologie et de Santé Publique, Labex DISTALZ, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Andrieu, Sandrine" sort="Andrieu, Sandrine" uniqKey="Andrieu S" first="Sandrine" last="Andrieu">Sandrine Andrieu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology and Public Health, Faculty of Medicine, Toulouse University Hospital, Toulouse, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Epidemiology and Public Health, Faculty of Medicine, Toulouse University Hospital, Toulouse</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Ballard, Clive" sort="Ballard, Clive" uniqKey="Ballard C" first="Clive" last="Ballard">Clive Ballard</name><affiliation wicri:level="3"><nlm:affiliation>Wolfson Centre for Age-Related Diseases, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wolfson Centre for Age-Related Diseases, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Brayne, Carol" sort="Brayne, Carol" uniqKey="Brayne C" first="Carol" last="Brayne">Carol Brayne</name><affiliation wicri:level="4"><nlm:affiliation>Cambridge Institute of Public Health, University of Cambridge, Cambridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cambridge Institute of Public Health, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Brodaty, Henry" sort="Brodaty, Henry" uniqKey="Brodaty H" first="Henry" last="Brodaty">Henry Brodaty</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing and Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Healthy Brain Ageing and Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Cedazo Minguez, Angel" sort="Cedazo Minguez, Angel" uniqKey="Cedazo Minguez A" first="Angel" last="Cedazo-Minguez">Angel Cedazo-Minguez</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name><affiliation wicri:level="3"><nlm:affiliation>Institut de la Mémoire et de la Maladie d'Alzheimer, IM2A, INSERM, Institut du Cerveau et de la Moelle Épinière, UMR-S975, Groupe Hospitalier Pitié-Salpêtrière, Université Pierre et Marie Curie-Paris 6, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut de la Mémoire et de la Maladie d'Alzheimer, IM2A, INSERM, Institut du Cerveau et de la Moelle Épinière, UMR-S975, Groupe Hospitalier Pitié-Salpêtrière, Université Pierre et Marie Curie-Paris 6, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Edvardsson, David" sort="Edvardsson, David" uniqKey="Edvardsson D" first="David" last="Edvardsson">David Edvardsson</name><affiliation wicri:level="1"><nlm:affiliation>School of Nursing and Midwifery, La Trobe University, Melbourne, VIC, Australia; Department of Nursing, Umeå University, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>School of Nursing and Midwifery, La Trobe University, Melbourne, VIC, Australia; Department of Nursing, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Feldman, Howard" sort="Feldman, Howard" uniqKey="Feldman H" first="Howard" last="Feldman">Howard Feldman</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Neurology, Faculty of Medicine, University of British Columbia, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Fratiglioni, Laura" sort="Fratiglioni, Laura" uniqKey="Fratiglioni L" first="Laura" last="Fratiglioni">Laura Fratiglioni</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Frisoni, Giovanni B" sort="Frisoni, Giovanni B" uniqKey="Frisoni G" first="Giovanni B" last="Frisoni">Giovanni B. Frisoni</name><affiliation wicri:level="1"><nlm:affiliation>Geneva University Hospitals and University of Geneva, Geneva, Switzerland; IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Geneva University Hospitals and University of Geneva, Geneva, Switzerland; IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia</wicri:regionArea><wicri:noRegion>Brescia</wicri:noRegion></affiliation></author><author><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name><affiliation wicri:level="1"><nlm:affiliation>McGill Center for Studies in Aging, Alzheimer's Disease Research Unit, and Douglas Mental Health University Institute, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McGill Center for Studies in Aging, Alzheimer's Disease Research Unit, and Douglas Mental Health University Institute, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Georges, Jean" sort="Georges, Jean" uniqKey="Georges J" first="Jean" last="Georges">Jean Georges</name><affiliation wicri:level="1"><nlm:affiliation>Alzheimer Europe, Luxembourg City, Luxembourg.</nlm:affiliation><country xml:lang="fr">Luxembourg (pays)</country><wicri:regionArea>Alzheimer Europe, Luxembourg City</wicri:regionArea><wicri:noRegion>Luxembourg City</wicri:noRegion></affiliation></author><author><name sortKey="Graff, Caroline" sort="Graff, Caroline" uniqKey="Graff C" first="Caroline" last="Graff">Caroline Graff</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Iqbal, Khalid" sort="Iqbal, Khalid" uniqKey="Iqbal K" first="Khalid" last="Iqbal">Khalid Iqbal</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research, Staten Island, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research, Staten Island, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Jessen, Frank" sort="Jessen, Frank" uniqKey="Jessen F" first="Frank" last="Jessen">Frank Jessen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry, University of Cologne, Cologne, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Psychiatry, University of Cologne, Cologne, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Johansson, Gunilla" sort="Johansson, Gunilla" uniqKey="Johansson G" first="Gunilla" last="Johansson">Gunilla Johansson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Jonsson, Linus" sort="Jonsson, Linus" uniqKey="Jonsson L" first="Linus" last="Jönsson">Linus Jönsson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Kivipelto, Miia" sort="Kivipelto, Miia" uniqKey="Kivipelto M" first="Miia" last="Kivipelto">Miia Kivipelto</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Knapp, Martin" sort="Knapp, Martin" uniqKey="Knapp M" first="Martin" last="Knapp">Martin Knapp</name><affiliation wicri:level="3"><nlm:affiliation>Personal Social Services Research Unit, London School of Economics and Political Science, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Personal Social Services Research Unit, London School of Economics and Political Science, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Mangialasche, Francesca" sort="Mangialasche, Francesca" uniqKey="Mangialasche F" first="Francesca" last="Mangialasche">Francesca Mangialasche</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Melis, Rene" sort="Melis, Rene" uniqKey="Melis R" first="René" last="Melis">René Melis</name><affiliation wicri:level="3"><nlm:affiliation>Radboudumc Alzheimer Centre and Department of Geriatric Medicine, Radboud University Medical Center, Nijmegen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboudumc Alzheimer Centre and Department of Geriatric Medicine, Radboud University Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Nordberg, Agneta" sort="Nordberg, Agneta" uniqKey="Nordberg A" first="Agneta" last="Nordberg">Agneta Nordberg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Translational Alzheimer Biology, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Translational Alzheimer Biology, Karolinska Institutet, Huddinge, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Rikkert, Marcel Olde" sort="Rikkert, Marcel Olde" uniqKey="Rikkert M" first="Marcel Olde" last="Rikkert">Marcel Olde Rikkert</name><affiliation wicri:level="3"><nlm:affiliation>Radboudumc Alzheimer Centre and Department of Geriatric Medicine, Radboud University Medical Center, Nijmegen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboudumc Alzheimer Centre and Department of Geriatric Medicine, Radboud University Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Qiu, Chengxuan" sort="Qiu, Chengxuan" uniqKey="Qiu C" first="Chengxuan" last="Qiu">Chengxuan Qiu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Aging Research Center, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Sakmar, Thomas P" sort="Sakmar, Thomas P" uniqKey="Sakmar T" first="Thomas P" last="Sakmar">Thomas P. Sakmar</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Laboratory of Chemical Biology & Signal Transduction, The Rockefeller University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Laboratory of Chemical Biology & Signal Transduction, The Rockefeller University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Scheltens, Philip" sort="Scheltens, Philip" uniqKey="Scheltens P" first="Philip" last="Scheltens">Philip Scheltens</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus, Amsterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Schneider, Lon S" sort="Schneider, Lon S" uniqKey="Schneider L" first="Lon S" last="Schneider">Lon S. Schneider</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry and the Behavioral Sciences and Department of Neurology, Keck School of Medicine, Leonard Davis School of Gerontology of the University of Southern California, Los Angeles, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry and the Behavioral Sciences and Department of Neurology, Keck School of Medicine, Leonard Davis School of Gerontology of the University of Southern California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Sperling, Reisa" sort="Sperling, Reisa" uniqKey="Sperling R" first="Reisa" last="Sperling">Reisa Sperling</name><affiliation wicri:level="2"><nlm:affiliation>Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Tjernberg, Lars O" sort="Tjernberg, Lars O" uniqKey="Tjernberg L" first="Lars O" last="Tjernberg">Lars O. Tjernberg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Waldemar, Gunhild" sort="Waldemar, Gunhild" uniqKey="Waldemar G" first="Gunhild" last="Waldemar">Gunhild Waldemar</name><affiliation wicri:level="3"><nlm:affiliation>Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Wimo, Anders" sort="Wimo, Anders" uniqKey="Wimo A" first="Anders" last="Wimo">Anders Wimo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge</wicri:regionArea><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Zetterberg, Henrik" sort="Zetterberg, Henrik" uniqKey="Zetterberg H" first="Henrik" last="Zetterberg">Henrik Zetterberg</name><affiliation wicri:level="3"><nlm:affiliation>Clinical Neurochemistry Laboratory, Department of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; UCL Institute of Neurology, Queen Square, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Neurochemistry Laboratory, Department of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; UCL Institute of Neurology, Queen Square, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></analytic><series><title level="j">The Lancet. Neurology</title><idno type="eISSN">1474-4465</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alzheimer Disease (therapy)</term><term>Biomedical Research (economics)</term><term>Biomedical Research (organization & administration)</term><term>Dementia (therapy)</term><term>Europe</term><term>Humans</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Démence ()</term><term>Europe</term><term>Humains</term><term>Maladie d'Alzheimer ()</term><term>Recherche biomédicale (organisation et administration)</term><term>Recherche biomédicale (économie)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Europe</term></keywords><keywords scheme="MESH" qualifier="economics" xml:lang="en"><term>Biomedical Research</term></keywords><keywords scheme="MESH" qualifier="organisation et administration" xml:lang="fr"><term>Recherche biomédicale</term></keywords><keywords scheme="MESH" qualifier="organization & administration" xml:lang="en"><term>Biomedical Research</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Alzheimer Disease</term><term>Dementia</term></keywords><keywords scheme="MESH" qualifier="économie" xml:lang="fr"><term>Recherche biomédicale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Démence</term><term>Europe</term><term>Humains</term><term>Maladie d'Alzheimer</term></keywords></textClass></profileDesc></teiHeader></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Canada</li><li>Danemark</li><li>France</li><li>Italie</li><li>Luxembourg (pays)</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li><li>Californie</li><li>District de Cologne</li><li>Grand Londres</li><li>Gueldre</li><li>Hauts-de-France</li><li>Hollande-Septentrionale</li><li>Hovedstaden</li><li>Massachusetts</li><li>Midi-Pyrénées</li><li>Nord-Pas-de-Calais</li><li>Occitanie (région administrative)</li><li>Rhénanie-du-Nord-Westphalie</li><li>Svealand</li><li>État de New York</li><li>Île-de-France</li></region><settlement><li>Amsterdam</li><li>Bonn</li><li>Cambridge</li><li>Copenhague</li><li>Lille</li><li>Londres</li><li>Los Angeles</li><li>Nimègue</li><li>Paris</li><li>Stockholm</li><li>Toulouse</li></settlement><orgName><li>Université de Californie du Sud</li><li>Université de Cambridge</li></orgName></list><tree><country name="Suède"><noRegion><name sortKey="Winblad, Bengt" sort="Winblad, Bengt" uniqKey="Winblad B" first="Bengt" last="Winblad">Bengt Winblad</name></noRegion><name sortKey="Cedazo Minguez, Angel" sort="Cedazo Minguez, Angel" uniqKey="Cedazo Minguez A" first="Angel" last="Cedazo-Minguez">Angel Cedazo-Minguez</name><name sortKey="Edvardsson, David" sort="Edvardsson, David" uniqKey="Edvardsson D" first="David" last="Edvardsson">David Edvardsson</name><name sortKey="Fratiglioni, Laura" sort="Fratiglioni, Laura" uniqKey="Fratiglioni L" first="Laura" last="Fratiglioni">Laura Fratiglioni</name><name sortKey="Graff, Caroline" sort="Graff, Caroline" uniqKey="Graff C" first="Caroline" last="Graff">Caroline Graff</name><name sortKey="Johansson, Gunilla" sort="Johansson, Gunilla" uniqKey="Johansson G" first="Gunilla" last="Johansson">Gunilla Johansson</name><name sortKey="Jonsson, Linus" sort="Jonsson, Linus" uniqKey="Jonsson L" first="Linus" last="Jönsson">Linus Jönsson</name><name sortKey="Kivipelto, Miia" sort="Kivipelto, Miia" uniqKey="Kivipelto M" first="Miia" last="Kivipelto">Miia Kivipelto</name><name sortKey="Mangialasche, Francesca" sort="Mangialasche, Francesca" uniqKey="Mangialasche F" first="Francesca" last="Mangialasche">Francesca Mangialasche</name><name sortKey="Nordberg, Agneta" sort="Nordberg, Agneta" uniqKey="Nordberg A" first="Agneta" last="Nordberg">Agneta Nordberg</name><name sortKey="Qiu, Chengxuan" sort="Qiu, Chengxuan" uniqKey="Qiu C" first="Chengxuan" last="Qiu">Chengxuan Qiu</name><name sortKey="Tjernberg, Lars O" sort="Tjernberg, Lars O" uniqKey="Tjernberg L" first="Lars O" last="Tjernberg">Lars O. Tjernberg</name><name sortKey="Wimo, Anders" sort="Wimo, Anders" uniqKey="Wimo A" first="Anders" last="Wimo">Anders Wimo</name></country><country name="France"><region name="Hauts-de-France"><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name></region><name sortKey="Andrieu, Sandrine" sort="Andrieu, Sandrine" uniqKey="Andrieu S" first="Sandrine" last="Andrieu">Sandrine Andrieu</name><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Ballard, Clive" sort="Ballard, Clive" uniqKey="Ballard C" first="Clive" last="Ballard">Clive Ballard</name></region><name sortKey="Brayne, Carol" sort="Brayne, Carol" uniqKey="Brayne C" first="Carol" last="Brayne">Carol Brayne</name><name sortKey="Knapp, Martin" sort="Knapp, Martin" uniqKey="Knapp M" first="Martin" last="Knapp">Martin Knapp</name><name sortKey="Zetterberg, Henrik" sort="Zetterberg, Henrik" uniqKey="Zetterberg H" first="Henrik" last="Zetterberg">Henrik Zetterberg</name></country><country name="Australie"><noRegion><name sortKey="Brodaty, Henry" sort="Brodaty, Henry" uniqKey="Brodaty H" first="Henry" last="Brodaty">Henry Brodaty</name></noRegion></country><country name="Canada"><noRegion><name sortKey="Feldman, Howard" sort="Feldman, Howard" uniqKey="Feldman H" first="Howard" last="Feldman">Howard Feldman</name></noRegion><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name></country><country name="Italie"><noRegion><name sortKey="Frisoni, Giovanni B" sort="Frisoni, Giovanni B" uniqKey="Frisoni G" first="Giovanni B" last="Frisoni">Giovanni B. Frisoni</name></noRegion></country><country name="Luxembourg (pays)"><noRegion><name sortKey="Georges, Jean" sort="Georges, Jean" uniqKey="Georges J" first="Jean" last="Georges">Jean Georges</name></noRegion></country><country name="États-Unis"><region name="État de New York"><name sortKey="Iqbal, Khalid" sort="Iqbal, Khalid" uniqKey="Iqbal K" first="Khalid" last="Iqbal">Khalid Iqbal</name></region><name sortKey="Sakmar, Thomas P" sort="Sakmar, Thomas P" uniqKey="Sakmar T" first="Thomas P" last="Sakmar">Thomas P. Sakmar</name><name sortKey="Schneider, Lon S" sort="Schneider, Lon S" uniqKey="Schneider L" first="Lon S" last="Schneider">Lon S. Schneider</name><name sortKey="Sperling, Reisa" sort="Sperling, Reisa" uniqKey="Sperling R" first="Reisa" last="Sperling">Reisa Sperling</name></country><country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Jessen, Frank" sort="Jessen, Frank" uniqKey="Jessen F" first="Frank" last="Jessen">Frank Jessen</name></region></country><country name="Pays-Bas"><region name="Gueldre"><name sortKey="Melis, Rene" sort="Melis, Rene" uniqKey="Melis R" first="René" last="Melis">René Melis</name></region><name sortKey="Rikkert, Marcel Olde" sort="Rikkert, Marcel Olde" uniqKey="Rikkert M" first="Marcel Olde" last="Rikkert">Marcel Olde Rikkert</name><name sortKey="Scheltens, Philip" sort="Scheltens, Philip" uniqKey="Scheltens P" first="Philip" last="Scheltens">Philip Scheltens</name></country><country name="Danemark"><region name="Hovedstaden"><name sortKey="Waldemar, Gunhild" sort="Waldemar, Gunhild" uniqKey="Waldemar G" first="Gunhild" last="Waldemar">Gunhild Waldemar</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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